Leadership Programs Train Skills. This One Trains the Brain Behind Them.
Sleep disruption, chronic stress, and emotional dysregulation erode decision-making, creativity, and resilience. Most leadership programs ignore these biological foundations. The Neuroscience of Optimal Performance course gives your leaders the science and practical tools to manage them. Built by PhD neuroscientists. A self-paced course your organization can implement tomorrow.
THE GAP IN LEADERSHIP DEVELOPMENT
The Neural Systems Underneath the Skills
$411B+
in annual U.S. productivity lost to insufficient sleep, projected to exceed $456B by 2030
RAND Corporation, 2016
18–43%
of leaders across our assessments report sleepiness levels associated with cognitive impairment
BBL data: 196 leaders across manufacturing, technology, and healthcare
#2 Skill
employers need by 2030: resilience, flexibility, and agility, cited by 67% of 1,000+ employers surveyed
World Economic Forum, Future of Jobs Report 2025
Organizations invest heavily in leadership training, but most programs skip the biological systems that determine whether those skills actually work under pressure. Sleep deprivation impairs cognitive performance as much as alcohol intoxication. Chronic stress shuts down the prefrontal cortex functions leaders depend on for judgment and impulse control. These are not skill gaps. They are neurobiological ones.
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The Neuroscience of Optimal Performance course targets these foundations directly, giving leaders measurable tools for sleep quality, stress regulation, and emotional performance, backed by the same peer-reviewed research your most skeptical executives will respect.
WHAT LEADERS WILL LEARN
3 Modules. 4–6 Hours. Immediate Application.
Each module targets a neurobiological system that directly affects how your leaders think, decide, and perform.

MODULE 1
The Neuroscience of Good Sleep
Why sleep quality directly shapes judgment, creativity, and emotional control the next day and over time. Leaders learn how sleep architecture works, why common habits are actively degrading their performance, and specific evidence-based strategies for optimizing sleep quality and timing.
MODULE 2
The Neuroscience of Moderate Stress
The right amount of stress sharpens performance. Too much shuts down the executive functions leaders need most. Leaders learn to recognize where they are on the stress curve in real time and apply practical regulation techniques before high-stakes meetings, difficult conversations, or high-pressure quarters.
MODULE 3
The Neuroscience of Positive Emotion
Positive emotion is not a soft skill. It is a measurable performance multiplier for innovation, creative problem-solving, and team dynamics. Leaders learn how emotional states shape cognitive performance and gain practical tools for cultivating and regulating emotional experience under real organizational pressure.
50+ video lessons
Short, focused segments taught by Jessica Payne, PhD and Christine Payne, PhD.
Self-assessments and branching scenarios
Adapted from established psychometric instruments, with real-world decision points and neuroscience-informed feedback.
Pre-post measurement
Measure knowledge gains and behavioral change across sleepiness, stress, anxiety, and positive emotion.
FLEXIBLE DEPLOYMENT
How Organizations Use This
Designed to fit your existing infrastructure and learning culture.
Licensed E-Learning
Deploy the NOP course through your LMS as a self-paced learning experience. Includes pre-post assessments and usage analytics. SCORM 1.2 compatible.
E-Learning + Live Office Hours
Add recurring virtual office hours with our founders so learners can ask questions, discuss application, and deepen their understanding of the science as they work through the course.
RECOMMENDED
Blended Program
Combine e-learning and virtual office hours with a live keynote or workshop for comprehensive leadership development that connects the science to your organization's specific challenges.
DETAILS
Technical Specifications
FORMAT
SCORM 1.2 packages
DURATION
4–6 hours self-paced across 3 modules
LEARNER SCALE
100 to 10,000+ seats
LMS INTEGRATION
Any SCORM-compliant LMS. Support included.
LANGUAGE
English with captions
VIDEO LESSONS
50+ short segments
CONTENT UPDATES
Included with annual license
IMPLEMENTATION
Deploy in days, not months
Common Questions
Can we pilot the course before committing to a full rollout?
Yes. We offer pilot licenses for organizations that want to evaluate the course with a smaller group before scaling.
What does licensing include?
Full course access for your specified number of learners, pre-post assessments, usage analytics, and LMS integration support. Live add-ons (virtual office hours, keynote, or workshop) are available at any tier.
Is there new content in development?
Yes. The current course covers sleep, stress, and emotion. Additional modules spanning the full B.R.A.I.N.â„¢ framework, including social cognition, empathy, and interpersonal neuroscience, are in development.
How is this different from typical leadership training?
Most leadership programs focus on skills, behaviors, and mindset. They overlook the neurobiological systems those skills depend on. This course trains the systems underneath: the sleep architecture, stress physiology, and emotional neuroscience that determine whether leaders can actually execute under pressure.
THE RESEARCHERS BEHIND THE WORK
Developed by Neuroscientists Who Work With Leaders

Jessica Payne, PhD
Founder & CEO
Harvard-trained cognitive neuroscientist and Professor at the University of Notre Dame. Director, Sleep, Stress, and Memory Lab. h-index: 44, 9,300+ citations, ~$5M in federal research grants. Kavli Fellow, National Academy of Sciences.

Christine Payne, PhD
Founder & President
NYU-trained social/affective neuroscientist. Postdoctoral fellow, NYU Langone Medical Center. Lecturer, University of Notre Dame. Lead Instructor, NeuroLeadership Institute.
Our founders have presented to leadership audiences at Morgan Stanley, AQR Capital Management, D.E. Shaw, Fiera Capital, BorgWarner, Meta, Allegis Group, Genentech, Northwell Health, Intermountain Health, Ohio Health, Keck Medicine of USC, Astellas Pharma, Blizzard Entertainment, and Notre Dame Football.
See What Your Leaders Will Experience
We will send you a content preview showing sample lessons, self-assessments, and the science behind each module. No commitment required.